Syndromes and a Century is a poem on screen: a film of ideas and visual tropes that upends conventional narrative expectations, not out of a simple desire to disconcert but to break through the carapace of normality, to give us the knight’s-move away from reality that the Russian formalists said was the prerogative of art. It’s a movie to be compared with the work of Antonioni - or Sergei Parajanov. Perhaps, with its freakiness and scariness in those hospital basement scenes, it is something that might have intrigued Kubrick. Perhaps the best antidote to [our present] gloom is the appearance of films like this one. Profoundly mysterious, erotic, funny, gentle, playful, utterly distinctive, it is the work of the Thai director and installation-artist Apichatpong Weerasethakul, who now has a claim to be approaching the league of Kiarostami and Haneke, one of modern cinema’s great practitioners.
—Peter Bradshaw, The Guardian.